Sakuta Azusagawa is a high school student simply trying to live a quiet life away from trouble, but his days take a completely absurd turn when he meets Mai Sakurajima, a famous model and actress on a career break, who wanders around the school library dressed as a sexy bunny. The reason for this madness? Mai suffers from the mysterious "Adolescence Syndrome": a bizarre phenomenon linked to youthful anxiety that is making her invisible to everyone, to the point that people are even starting to forget she exists. Sakuta, touched by this problem firsthand due to past traumas he has experienced, decides to step in and help her at all costs. Between temporal anomalies, body swaps, clones, and the merciless psychological dramas that affect various girls around him, our protagonist defies logic to protect the people he cares about, confronting the darkest and most hidden wounds of adolescence.